Anpo was born and raised on the Pine Ridge Reservation in South Dakota, and earned her B.S in Environmental Systems Engineering and her M.S in Civil and Environmental Engineering from Stanford University, where she was the first Native woman on Stanford’s Student Global Health Board. As a writer, author, and poet, she interweaves her experiences as an Oglala woman, engineer, tribal college adjunct instructor and advocate for Indigenous solutions in global health & climate change in her creations.

Some of her advocacy roles have included being an Environmental Health Specialist for the International Indian Treaty Council, a youth representative of the Black Hills Sioux Nation Council, and North American Focal Point of the UN Global Indigenous Youth Caucus. In these capacities, she has delivered testimony on the United Nations floor that led to formal policy recommendations on Indigenous languages & health from the UN Permanent Forum on Indigenous Issues to the World Health Organization (WHO). Additionally, she was nominated and selected to serve on the first Youth cohort at the International Conference on Chemicals and Waste Management in Bonn, Germany. 

Her work has been featured in & by Forbes Magazine, the Native American 40 under 40 list, Scope, Grist, the UN Youth Envoy, the Oxford Climate Review, The Lancet, Stanford’s Center for Innovation in Global Health, the Journal of Climate Change and Health, and more.